Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages
Abstract A chronic low-grade inflammation within adipose tissue (AT) Urinary Drainage Bags seems to be the link between obesity and some of its associated diseases.One hallmark of this AT inflammation is the accumulation of AT macrophages (ATMs) around dead or dying adipocytes, forming so-called crown-like structures (CLS).To investigate the dynami